https://github.com/AppImage/AppImageKit/wiki/Bundling-Windows-applicati…
For 64-bit WINE on 64-bit Linux this is relatively straightforward. Here is an example, made by a third party, without our help: http://www.wildmediaserver.com/download.php (not developed by us) offers Linux versions which are basically Windows versions that bundle a minimal WINE subset.
But this approach will only be able to run 64-bit Windows executables, which are not always available, especially for legacy software that is often the reason for using WINE. Hence we will focus on 2.